Quick facts

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Safety: Taurine is considered safe for most people when taken as a supplement in recommended doses. Studies have shown that even high doses of taurine for extended periods (up to several grams per day) do not result in significant side effects or toxicity. The most commonly recommended doses in studies range from 1 to 3 grams per day; doses up to 6 grams per day for short periods have been used without apparent harm. Always consult with a trusted healthcare provider before starting any new supplement, especially if you have underlying health conditions or are taking other medications.

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ITP results: Not included

(The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice)

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Key trials: 

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Moludi J, Qaisar SA, Kadhim MM, Ahmadi Y, Davari M. Protective and therapeutic effectiveness of taurine supplementation plus low calorie diet on metabolic parameters and endothelial markers in patients with diabetes mellitus: a randomized, clinical trial. Nutr Metab (Lond). 2022 Jul 23;19(1):49. doi: 10.1186/s12986-022-00684-2. Erratum in: Nutr Metab (Lond). 2022 Sep 9;19(1):62. PMID: 35870947; PMCID: PMC9308194.

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Abud GF, De Carvalho FG, Batitucci G, Travieso SG, Bueno Junior CR, Barbosa Junior F, Marchini JS, de Freitas EC. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70. Nutrition. 2022 Sep;101:111706. doi: 10.1016/j.nut.2022.111706. Epub 2022 Apr 22. PMID: 35700594.

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Some studies and publications: 

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https://www.science.org/doi/10.1126/science.abn9257 : Taurine deficiency as a driver of aging

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Santulli, G.; Kansakar, U.; Varzideh, F.; Mone, P.; Jankauskas, S.S.; Lombardi, A. Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview. Nutrients 2023, 15, 4236. https://doi.org/10.3390/nu15194236

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Sheikh A, Iqbal M. Taurine as a potential anti-ageing therapy: the key to reversing the ageing process? Short communication. Ann Med Surg (Lond). 2023 May 20;85(7):3759-3760. doi: 10.1097/MS9.0000000000000826. PMID: 37427216; PMCID: PMC10328712.

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Overview: Taurine plays a role in several essential body functions, such as bile salt formation, eye health, heart function, and the development and function of skeletal muscle, the central nervous system, and the cardiovascular system. Its wide-ranging roles in cellular and physiological processes could influence both aging and lifespan.

https://www.cnbc.com/2023/08/25/taurine-supplements-may-lengthen-lifespan-heres-what-research-shows.html#:~:text=Mice%20that%20received%20taurine%20supplements,the%20study%2C%20told%20BBC%20News.

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Type of substance: Taurine is an amino sulfonic acid, which is a required building block of protein. It’s found naturally in the body and in meat, fish, and dairy products

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Other related: ALA Alpha Lipoic Acid, Fisetin, Urolithin, Glutathione

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