Quick facts

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Safety: Dasatinib is a chemotherapy drug with specific medical indications and potential side effects, while quercetin is a dietary flavonoid. Taking these substances together for the purpose of longevity or healthspan extension should only be considered under the guidance of a healthcare professional to ensure safety and adequacy for individual health conditions.

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ITP results: Not included

(The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice)

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Key trials: 

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Yu Sun, Qingfeng Li, James L Kirkland, Targeting senescent cells for a healthier longevity: the roadmap for an era of global aging, Life Medicine, Volume 1, Issue 2, October 2022, Pages 103–119, https://doi.org/10.1093/lifemedi/lnac030

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(see also Quercetin page)

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Some studies and publications: 

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Islam MT, Tuday E, Allen S, Kim J, Trott DW, Holland WL, Donato AJ, Lesniewski LA. Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age. Aging Cell. 2023 Feb;22(2):e13767. doi: 10.1111/acel.13767. Epub 2023 Jan 13. PMID: 36637079; PMCID: PMC9924942.

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(see also Quercetin page)

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Overview: The combination of dasatinib and quercetin has been studied for its potential to act as a senolytic therapy, targeting and eliminating senescent cells which accumulate with age and can contribute to age-related diseases.

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Type of substance: Dasatinib is a chemotherapy drug with specific medical indications and potential side effects, while quercetin is a dietary flavonoid. 

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Other related: quercetin, urolithin

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